Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep365 | Thyroid | ECE2024

Tocilizumab for the treatment of active steroid-resistant graves’ orbitopathy - 2 case reports from a romanian endocrinology department

E Ranetti Aurelian , Smeureanu Florentina , Andreea Creanga

Purpose: To describe pre- to post-treatment changes in clinical activity score (CAS) in patients with Graves orbitopathy treated with tocilizumab (TCZ).Introduction: GravesÂ’ ophthalmopathy (GO) is an autoimmune disorder that affects 30-50% of patients with GravesÂ’ disease. The first-line treatment of moderate to severe GO according to EUGOGO is intravenous glucocorticoids, but 20-30% of the cases appear to be corticosteroid refractory. Steroid-...